: Ankara University, Faculty of Science,
Department of Biology,   Ankara - Turkey

“Regulation of IgE synthesis by CD23 receptor on Follicular Dendritic cells”. Virginia Commonwealth University, Medical College of Virginia, Department of Immunology. Richmond – Virginia,USA. August 1997- June 1998.

• Deputy Director of GEBI : 2003 – 2009
• Acting Director of GEBI : 2009 – cont.

COURSES TAUGHT

1. Molecular immunology : Istanbul Technical University. 2002 – 2003, Undergraduate level
2. Molecular immunology : Gebze  Institute of Technology . 2001 - 2002, Graduate level
3. Molecular immunology : Gebze  Institute of Technology. 2000 - 2001, Graduate level
4. Molecular immunology : Gebze  Institute of Technology. 1999 - 2000, Graduate level

RESEARCH  FUNDS

1. Development of diagnostic kits for Hepatitis B infection by using serological and molecular techniques. Granted by TUBITAK – KAMAG 1007. (2006 – cont.) (Project manager)
2. Investigation of effects and molecular mechanisms of therapeutic immunizations on cellular immunity in an environment where tolerance to HBV antigens has developed. Granted by TUBITAK 1001 Programme. (2009 – cont). (Research assoc.)
3. Antiangiogenic anticancer applications of monoclonal antibodies: In vitro and in vivo studies in a hepatocellular carcinoma model. Granted by TUBITAK – SBAG (2002 – 2006.)  (Research assoc.)
4. The use of anti-idiotypic antibodies for the development of vaccine to Hepatitis virusB Granted by TUBITAK- SBAG. (2002- 2004). (Project manager)
5. Production of monoclonal antibodies against Verticillium wilt agent (Verticillium dahliae Kleb.) and diagnostic kit preparation. Granted by TUBITAK- TOGTAG-TARP. (2002 ) (Research assoc.)
6. Modification of Aluminum adjuvant  vaccines by Monoclonal Antibodies. Granted by Eczacıbaşı Company. (1999 - 2000 ). (Project manager)
7. Regulation of allergic response by CD23 on FDC cells. Virginia Commonwealth University, Medical College of Virginia, Department of Immunology, Richmond, Virginia USA. (08 / 1997 – 06 / 1998).  (Postdoctoral fellow/researcher)
8. Preparation of Immune Diagnostic Kits based on Hepatit B Polypeptides: Production of monoclonal antibodies against Hepatit B virus. Granted by BİOMAR Company.(1997-2000) (Research assistant)
9. Monoclonal  Antibodies –  Modification  by  Recombinant  DNA  Technology   and Exploitation. Granted by NATO SFS-TU Biotech II . (1994-1998). (Research assistant)
10. Biotechnology – Establishment and Promotion of New Biotechnological Techniques   in Turkey. Granted by NATO - SFS- TU  Biotech I.  (1988-1993). (Research assistant)
11.  Establishment of Hybridoma, Recombinant DNA and Transgenic Technology in Gebze- TUBİTAK.  Granted by UNIDO (TUR/87/042). (1987 - 1993).  (Research assistant)

1. Basalp A. Modulation of the humoral immune response to aluminum adjuvanted HBV vaccine by antigen specific monoclonal antibodies. Current Topics in Virology. vol.6:25-32, 2007
2. Basalp A, Yucel F, Kumbasar A, Baysal K. MAbs against vascular endothelial growth factor receptor (KDR). Hybridoma. 25(4):249-250, 2006
3. Yucel F, Ozturk S,  Erdag B, Balcioglu K, Basalp A, Baysal K. MAbs against vascular endothelial growth factor. Hybridoma. 25(2):98 – 100, 2006
4. Yucel F, Benlioglu S, Basalp A, Ozturk S, Benlioglu K. Development of a double monoclonal antibody sandwich ELISA test for Verticillium dahliae Kleb. Food and Agricultural immunology. 16(1-4): 283 – 291, 2005
5. Yıldırım T, Basalp A, Yucel F, Manav AI, Sezen IY. Generation  of anti-idiotypic antibodies that mimick HBsAg and vaccination against Hepatit B Virus . Hybridoma and Hybridomics. 23(3):192-197, 2004
6. Basalp A, Yucel F. Development of mouse hybridomas by fusion of myeloma cells with lymphocytes derived from spleen, lymph node and bone marrow. Hybridoma and Hybridomics. 22(5):329-331, 2003
7. Yucel F, Manav I, Basalp A. Production and Characterization of  Monoclonal Antibodies Against Hepatitis B Viruses and Application of a Quick  Sandwich ELISA. Hybridoma and Hybridomics. 22(3):173-177, 2003.
8. Basalp A. Monoclonal antibodies against Hepatitis B Virus surface antigen. Hybridoma and Hybridomics .  21 (1) : 81-82, 2002 .
9. Basalp A, Mustafaeva Z, Mustafaev M. Cu2+ induced Biopolymer systems comprising a steroid hormone, protein antigen and synthetic polyelectrolytes . Hybridoma and Hybridomics 21 (1) : 45-51, 2002
10. Payet-Jamroz M, Helm SLT, Wu J, Kilmon M, Fakher M, Basalp A, Tew JG, Szakal AK, Noben-Trauth N. Conrad DH. Suppression of IgE Responses in CD23 Transgenic Animals Is Due To Expression of CD23 on Non-Lymphoid Cells. J.Immunol. 166:4863-4869, 2001
11. Basalp A,  Mustafaeva Z, Mustafaev M, Bermek E.  Immune response to 17 beta-estradiol involved in polymer gels: antigen specificity and affinity of hybridoma clones.  Hybridoma 19(6):495-499, 2000
12. Basalp A,  Cirakoglu B,  Bermek E. Enhancement of the immune response to Hepatitis   B virüs vaccine by antigen specific IgM. Immunol. Letters. 73:1-6, 2000
13. Basalp A, Cirakoglu B, Bermek E. Simple way for the production and purification of monoclonal antibodies in serum-free medium. Tr. J. Biol. 24:189-196, 2000
14. Accoto G P, Adam G, Alioto D, Basalp A, Bech K, Cuperus C, Dellavalle D, Desbiez C, Grassi G,  Hellwald K H,  Katis N, Lecoq H, Lisa V,  Luis-Artega M,  Lusioni E, Miller A, Moriones E,  Nolasco G,  Rabenstein F, Roggero P, Tomassoli L, Torrance L,.van der Vlugt R, Vaira A M, Vetten J, Winter S. Detection and Biodiversity of Cucumber Mosaic Cucumovirus.Conclusions from a ringtest of European Union Cost 823 (New technology to improve phytodiagnosis). J.Plant Pathol. 80(2):133-149. 1998
15. Mustafaev M, Osada Y,  Basalp A, Mustafaev Z, Cirakoglu B, Bermek E. New  temperature immunogens by poly(N-isopropylacrylamide)-modified bovine serum albumin.Recent Advences in Peptide and Protein Delivery . Editions de Santé. Paris-France, 1998.
16. Basalp A, Yorganci U, Cirakoglu B,  Bermek E. Detection of Tobacco Mosaic virus by monoclonal antibody MAM-1F5. Tr. J. Biology . l.21:397-403. 1997
17. Basalp A,  Bermek E, Cirakoglu B, Coka V,  Mustafaev M I,  Sarac A S. Immune response  to 17ß-Esatradiol in polyelecrolyte complex: Antigen specifıcity and affinity of hybridoma clones. Hybridoma. 15 (3) : 233 - 238 . 1996
18. Mustafaev M, Osada Y,  Matsukata M,  Basalp A,  Cirakoglu B,  Bermek E. New amphilic immunogens by poly(N-Isopropylacrylamide)-modified bovine serum albumin. Polymer gels and networks.  4:363-372. 1996
19. Basalp A, Cirakoglu B, Bermek E. A simple and accurate way for diagnosis of Erwinia car.subs.atroseptica. Tr.J. Biology . 19:323-329. 1995
20. Yucel F, Basalp  A,  Cirakoglu B, Bermek E. Monoclonal antibodies MAM 6F3. Hybridoma.  14(5):501-502. 1995
21. Basalp A, Ozcengiz G,  Alaeddinoglu N G. Changes in patterns of alkaline serine protease and bacilysin formation caused by common effectors of sporulation in bacillus subtilis 168. Current Microbiology.  24:129-135. 1992
22. Basalp A, Yucel F, Cirakoglu B,  Benlioglu K,  Bermek E. Monoclonal antibody MAM-3A3 (anti Erwinia caratavora subs.atroseptica ). Monoclonal antibodies. 10(4):1-3. 1992
23. Basalp A, Ozcengiz G, Alaeddinoglu N G. A rapid plate test for screening of hyperproducer mutants of alkaline serin protease. Biokimya Dergisi. XV(1):19-25 . 1990

1. Hatipoglu I, Soğut I, Akcael E, Manav AI, Kocaaga H, Yucel F, Basalp A. Production and characterization of monoclonal antibodies against rHBeAg. Third International Congress of Molecular Medicine. Istanbul – Turkey , 5-8 May 2009
2. Başalp A. Antibody-mediated modulation of the immune response to Hepatitis B virus vaccine. Europe – Africa Frontier Research Conference Series. Infectious Diseases: From Basic to Translational Research. Cape Town – Republic of South Africa, 4 – 9 April 2009
3. Sogut I,   Hatipoglu I, Akcael E, Manav AI, Kocaaga H, Yucel F, Basalp A. Production of Monoclonal Antibody Against r-HBeAg and Development of  Serological Diagnostic Kit . 34th FEBS Congress .  Prag – Republic of Czech , 04-09 July 2009
4. Akcael E, Manav AI, Basalp A, Yucel F. Comparison of Diagnostic Kits Developed with Two Different  Labeled-Antibodies for the Detection of HBsAg. 34th FEBS Congress.  Prag - Republic of Czech ,  04-09 July 2009
5. Balcioglu K, Ozdemir A,  Hatipoglu I, Sogut I, Basalp A, Erdag B. Expression of hepatitis B surface antigene on phage as piii fusion protein. XIV. International congress of Virology. Istanbul – Turkey, 10 – 15 August 2008
6. Sogut I, Hatipoglu I, Ozdemir A, Balcioglu BK,  Erdag B, Basalp A.. Generation of M13 phage specific monoclonal antibody by  HBe antigen expressing phage immunization. 33rd FEBS Congress & 11th IUBMB Conference. Athens – Greece, 28 June – 3 July 2008
7. Basalp A.  The Influence of Adjuvant on The Immune Response And Specificity of Monoclonal Antibodies.  7th EFIS Tatra immunology congress. Strebsko Pleso, Slovakia. 24-28 June 2006
8. Basalp A, Yucel F, Kumbasar A, Baysal K.Development and Characterization of Monoclonal Antibodies to VEGFR2. 31st FEBS Congress. Istanbul - Türkey, 24 - 29 June 2006.
9. Yucel F, Ozturk S, Kumbasar A, Serhatli M, Erdag B, Balcıoglu K, Basalp A, Baysal K. Production of monoclonal antibodies against Vascular Endothelial Growth Factor. 31st FEBS Congress. Istanbul - Turkey, 24 - 29 June 2006.
10. Erdag B, Balcıoglu K, Ozdemir A, Yucel F, Basalp A, Cirakoglu B. Cloning of anti-HBsAg variable fragments for targeted intracellular immuntheraphy. 2nd ISC. International Coference on Cancer  Terapeutics. Istanbul – Turkey, 10 – 12 November 2005
11. Basalp A. Monoclonal Antibody Mediated-Modulation of the Humoral Immune Response to HBV Vaccine.  New Approaches to Vaccine Development: From the bench to the field. Berlin- Germany , 8-10 September 2005
12. Yildirim T, Akkor M, Yucel F, Basalp A. Effect of purification conditions on the specificity of anti-idiotypic antibodies. 4th. Balkan Congress of Immunology. Istanbul-Turkey, 5-8 September 2004
13. Ozturk S, Kumbasar A, Yucel F, Basalp A, Baysal K, Cirakoglu B. Production and characterization of monoclonal antibodies that block binding of Vascular Endothelial Growth factor (VEGF) to VEGF receptor for inhibition of solid tumor vascularization. European conference on biopharmaceutical antibodies. Cannes- France, 20-22 October 2003
14. Basalp A, Yucel F, Kumbasar A, Baysal K. Function blocking antiboides against human vascular endothelial growth factor: production  and characterisation. 28th Meeting of FEBS. Istanbul – Turkey, 20 – 25 October 2002
15. Basalp A. Regulation of immune response to Hepatit B virüs vaccine by monoclonal antibodies. 1st International and 2nd national workshop on vaccine adjuvants. Havana – Cuba, 5 – 8 December 2001
16. Basalp A, Yucel F,  Mustafaev M, Bermek E. Polyelectrolyte complexes as  alternative adjuvants for estradiol and progesterone. 1st International Biosciences days. Antalya - Turkey,   20- 24 April  1999
17. Helm S,  Basalp A, Szakal A,  Condrad D,  Tew J G. FDC-CD23 and regulation of IgE production  Dendritic cells . New Candidates for Therapeutic development for cancer and Infectious diseases.  Baltimore -Maryland -U.S.A, 29-30 January 1998
18. Basalp A,  Cirakoglu B,  Mustafaev M, Bermek E.The use of polyelectrolyte complex as a carrier for 17 ß-estradiol. First Japanase -Turkish workshop. Gebze -Turkey, 16-19 September  1998

PATENTS

1. Mustafaev M,  Basalp A, Mustafaeva Z, Nagieva I, Bermek E. Immunogenic beta-estradiol comprising polymer gels. TR   1999    01945 B
2. Mustafaev M, Yucel F,  Basalp A, Mustafaeva Z, Cirakoglu B, Bermek E . Immune response to progesterone immobilizing on Cu2+- induced polyelectrolyte-protein complex: antigen specificity and affinity of hybridoma clones. TR  1999   02290 B  
3. Mustafaev M, Basalp A, Yucel F, Cirakoglu B, Bermek E. Three-component immunogen comprising a protein, steroid hormone and a polycationic polyelectrolyte. Patent No:  TR   1997   00395 B.

COURSES

1. JRC Enlargement And Integration Workshop Alternatives 2005 - International Workshop on Promotion of the Three Rs (Reduction, Refinement, Replacement) Concept in Relation to Animal Experimentation in Croatia, Turkey and Western Balkan Countries. Ljubljana, Slovenia.  18 – 20 September 2005 .
2. 1st Latin American course of immune response induction. Havana-Cuba. 10-12 December 2001.
3. Techniques in Molecular and Cellular Immunology.  New Delhi – India.  6-17  November 2000.
4. Basic Immunology course. Bursa-Turkey.  26 - 28 November 1998.
5. Zucchini Viruses Ringtest . EU Cost Action. Torino - Italy. 19 - 22 October 1996.
6. Protein purification and characterization . Izmir -Turkey. 22- 28 September 1996.

1. Scholarship.  TUBITAK  (During M.S )  (1986 - 1988 )
2. Postdoctoral Fellowship:TUBITAK–NATO Science Fellowship Programme. (September 1997 – February 1998 )
3. Grant: TÜBİTAK – MAM. World Bank (Technical training). (March – June 2001)
4. Grant: ICGEB (For accommodation and living expenses during course) (November,  2000)
5. Grant: TUBITAK- BAYG  (For travelling)   (December 2001)
6. Grant: TUBITAK- 6FP Programme (For travelling and living expenses) ( November 2002)
7. Grant: Heidelberg Univ.  (For travelling and living expenses) (March 2003)
8. Grant: TUBITAK- 6FP Programme (For travelling and living expenses) ( May 2003)
9. Grant: JRC Enlargement actIon – IHCP W11   (For travelling and living and living expenses) (September 2005)